Rejuve Anti Aging Medical Spa in Rancho Santa Margarita

STEM CELL JOINT INJECTIONS

SPINE & BACK PAIN

STEM CELL JOINT INJECTIONS

SPINE & BACK PAIN

Regenerative medicine treatments may offer a superior alternative to spine surgery

Rediscover youthful mobility and flexibility with Rejuve Anti Aging’s cutting-edge regenerative therapies. Our advanced trifecta joint injections—featuring PRP, Stem Cells, and Exosomes—offer a sophisticated, non-surgical solution to address spine pain and related injuries.

By harnessing your body’s innate healing abilities, these innovative treatments stimulate natural tissue repair and regeneration. They effectively target common spinal issues such as arthritis, disc degeneration, ligament injuries, and nerve compression, offering long-term relief. Unlike traditional treatments that only mask the pain, our regenerative therapies address the root cause, promoting healing and restoring function to your spine.

Whether you’re an athlete looking to stay at your best, someone dealing with chronic spinal discomfort, or simply aiming to maintain peak mobility as you age, Rejuve’s regenerative solutions can help you regain strength, flexibility, and freedom from pain. Experience a revitalized, pain-free life, and potentially delay—or even avoid—the need for costly, invasive surgeries.

Skip the long recovery times and risks of traditional spine surgery. Rejuve Anti Aging offers ultrasound-guided stem cell injections, a precise, image-guided approach that uses your own Mesenchymal Stem Cells to repair damaged spinal tissues. This innovative treatment promotes natural healing and restored function, bypassing the risks and drawbacks associated with conventional surgical procedures.

Take the first step toward a pain-free spine. Contact Rejuve Anti Aging today to learn more about how our regenerative therapies can help you achieve lasting relief and better spinal health.

Spinal Stenosis - Herniated Discs - Sacroiliac Joint

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PROVEN RESULTS

Stem cell therapy: clinically proven to reduce joint pain and improve mobility.

NATURAL & SAFE

Leveraging the body’s own processes combined with PRP, Stem Cells and Exosomes

SIMPLE 30 MIN PROCEDURE

Ultrasound guided, highly accurate joint injections without anesthesia or downtime.

100% GUARANTEE OF SPINE PAIN REDUCTION!

Details Available During The Consultation

Clinical Studies of Stem Cells and Back & Spine Injuries​

Over the past decade, research and publications on the therapeutic application of mesenchymal stem cells (MSCs) for back and spine injuries have significantly increased. This expanding body of work underscores the strong interest and continuous advancements in refining and optimizing this innovative treatment approach.

Recent studies have increasingly focused on understanding the precise mechanisms of MSCs, moving beyond their ability to differentiate into various cell types to explore their critical roles in paracrine signaling and immunomodulation. This deeper insight has led to more targeted and effective applications in regenerative medicine for spinal conditions.

The growing number of clinical trials investigating MSC therapy for back and spine injuries reflects a dedicated effort to translate promising preclinical findings into real-world benefits for patients suffering from chronic pain, degenerative disc disease, spinal cord injuries, and other debilitating conditions.

"Researchers found a pain reduction greater than 50 percent at 12 months"

Emory University

A single injection of stem cells into degenerative discs reduced low back pain for at least 12 months

"Mesenchymal Stem Cells in the Treatment of Paralysis .. "

Mayo Clinic

Participants demonstrated improvement, with each moving up at least one AIS grade

"A study of 303 patients using stem cells for lower back pain"

British Medical Bulletin – Oxford Academic

Demonstrate that intradiscal injections of MSCs are effective on discogenic low-back pain

End Spine & Back Pain!

Have you been told that the only way to relieve your back pain is through steroid injections or invasive surgery?

Studies show that many traditional spine surgeries, such as disc fusions or spinal decompressions, often provide no greater benefit than placebo treatments. This raises concerns about their effectiveness in relieving pain and improving function over time.

While surgery may still be necessary for some severe spine conditions, these procedures are highly invasive and come with significant risks. The extensive rehabilitation required and the potential for accelerated degeneration in surrounding spinal structures can worsen long-term issues. This calls into question the appropriateness of these invasive surgeries, especially when considering non-surgical alternatives that can address the root cause of pain and improve mobility without the need for complex procedures.

At Rejuve Anti Aging, we offer regenerative therapies that can help you manage spine and back pain more effectively, providing lasting relief without the risks and downtime of surgery. Let us guide you toward better spine health with treatments like PRP, Stem Cells, and Exosomes, which promote natural healing and tissue regeneration.

Stem Cell Therapy Could Be The Exact Non-Surgical Alternative You’ve Been Waiting For!

Reclaim your active lifestyle. Rejuve Anti-Aging offers non-surgical solutions to get you back to the activities you love.

The fear is real: a sudden, sharp pain in your back, a misstep, or a painful spasm. The uncertainty of each movement keeps you on edge, causing you to second-guess even the simplest actions. Imagine missing out on life’s most precious moments—avoiding family gatherings, hesitating to take a walk, or staying home because you’re afraid of your back giving out.

For months, the pain, stiffness, and discomfort have held you back, making even everyday tasks feel daunting. The looming thought of invasive surgery, with its long recovery times and uncertain results, only adds to your anxiety. But what if there was another way?

At Rejuve Anti Aging, we understand the frustration and fear that come with chronic back and spine pain. That’s why we offer advanced, non-surgical regenerative therapies designed to support your body’s natural healing process. With innovative treatments like PRP, Stem Cells, and Exosomes, we help restore your spine’s health, providing relief, stability, and mobility—so you can live pain-free and return to your active lifestyle without the fear of surgery.

Let us help you regain your confidence and freedom with cutting-edge, effective treatments. It’s time to take control of your back health and move forward with strength and vitality.

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Outcomes For Spine & Back Stem Cell Procedures

Function Regained
0 %
Decrease In Pain 1 Month
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Overall Improvement 3 Months
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COMMON BACK & SPINE CONDITIONS TREATED WITH STEM CELL JOINT INJECTIONS AT REJUVE ANTI AGING

  • Spinal Stenosis

     

    If you're experiencing persistent back pain, spinal stenosis could be the underlying cause. While back pain is common, when it lasts and limits mobility, it might go beyond typical muscle strain or poor posture. Spinal stenosis, especially common in individuals over 50, involves the narrowing of spaces within the spine. This narrowing can put pressure on the nerves, leading to discomfort that may radiate into the arms or legs.

    Unlike typical back pain, spinal stenosis tends to worsen over time, especially with extended activity. The condition develops when the spaces within the spine narrow, placing pressure on the nerves that pass through the spinal canal. The spinal canal is a central opening in each vertebra, which houses and protects the spinal cord and branching nerves.

    When this space becomes constricted, nerve function can be compromised, causing a range of symptoms. These changes are often linked to alterations in the surrounding structures, making spinal stenosis a complex condition that requires a personalized approach to treatment.

    At Rejuve Anti Aging, we take a comprehensive approach to managing spinal stenosis. Traditional treatments like physical therapy and pain management may help, but we also offer advanced options like regenerative therapies, including stem cell treatments, designed to promote healing and reduce symptoms. These innovative, less-invasive procedures can help improve function and provide relief from the discomfort associated with spinal stenosis.

  • Sacroiliac (SI) Joint ​

     

    At Rejuve Anti Aging, we understand the challenges that come with injuries to the sacroiliac (SI) joint, a critical area where the hip and lumbar spine connect. Traditional treatment options, such as high-dose steroid injections, are commonly used but come with significant drawbacks. These injections may provide temporary relief, but they carry risks of side effects and do not address the root cause of the problem.

    Another option is SI fusion surgery, which aims to stabilize the joint by permanently joining the bones together. However, this procedure effectively removes the layer of shock absorption between the hip and lumbar spine, leading to increased stress on these areas. Over time, this can cause further damage and result in additional complications. In fact, studies show that 16.5% of patients who underwent lower back fusion surgery needed another surgery within five years to correct damage caused by the fusion. After 10 years, nearly a third of patients required another surgery. Furthermore, 55% of patients in a separate study were still relying on narcotics two years after the surgery, highlighting the long-term challenges and risks associated with this invasive approach.

    At Rejuve Anti Aging, we believe in exploring less invasive, regenerative treatment options that can help manage SI joint pain and promote healing. Our advanced regenerative therapies, including stem cell treatments, are designed to encourage natural healing, restore function, and reduce pain without the need for invasive surgeries or medications that carry long-term side effects. If you're struggling with SI joint pain or have concerns about traditional treatments, we're here to offer safer, more effective alternatives.

     
  • Herniated Disc Repair Without Surgery​

     

    The discs in your spine act as shock absorbers between your vertebrae. These discs have a tough outer layer, known as the annulus fibrosus, which encases a soft, gel-like substance called the nucleus pulposus.

    A herniated disc occurs when the outer layer ruptures, allowing the gel-like material to leak out. This can put pressure on and irritate nearby spinal nerves or the spinal cord, resulting in localized pain at the site of the disc and radiating pain, tingling, numbness, or weakness that may spread to the arms and legs.

    While often referred to as slipped or ruptured discs, herniated discs are different from disc bulges or protrusions, where the gel-like material remains contained within the disc.

    Traditional treatment options may include acupuncture, physical therapy, prescription medications, or high-dose epidural steroid injections. While steroid injections can offer temporary relief, they often come with side effects and can hinder your body's natural healing process.

    If conservative treatments don’t provide relief, surgery may be considered. The most common procedures involve removing part of the disc, which can weaken the disc and increase the risk of future injury. In more severe cases, spine fusion surgery may be recommended, permanently joining two vertebrae with hardware. However, this is an invasive solution and can limit spinal mobility.

    At Rejuve Anti Aging, we explore innovative, non-invasive treatments to help you find lasting relief without the need for surgery.

     

SPINAL JOINT HEALTH

The human body is designed to heal itself. Your body’s natural goal is repair and regeneration. A simple example is when you get a cut—your body stops the bleeding, forms a scab, and sends healing cells to close the wound.

This self-healing ability is constantly at work, even when you can’t see it. Your body is always scanning for damage and sending repair cells where they’re needed. However, certain factors influence how effectively your body can heal, including:

  • Smoking habits
  • Alcohol consumption
  • Sleep quality and duration
  • Regular physical activity
  • Nutrition and digestion
  • Stress management

Even with a healthy lifestyle—eating well, exercising, and getting enough rest—there are times when your body needs extra support. That’s where regenerative therapies at Rejuve Anti Aging can help. Our advanced treatments, including stem cell therapy and PRF, work with your body’s natural healing processes to restore function, reduce pain, and promote long-term wellness.

AND THAT’S WHERE REJUVE ANTI AGING CAN HELP!

REGENERATIVE MEDICINE FOR BACK & SPINE PAIN

Modern medicine often relies on medications that only mask pain rather than addressing the root cause of your discomfort. Too many individuals are pushed toward invasive surgeries that may not effectively resolve their pain or treat the underlying issues.

Surgery itself is a highly invasive procedure, often requiring tools and techniques more suited for construction than the human body. Recovery can take months or even years, and in many cases, the joint never fully regains its original function or feel.

Spinal surgeries often involve introducing foreign materials into the body, which can cause long-term complications. Much like how your body reacts to a splinter—attempting to push it out—your immune system may respond to implants with inflammation and pain, as it recognizes them as foreign.

At Rejuve Anti Aging, we believe in a different approach. Our regenerative therapies work in harmony with your body’s natural healing processes. Using cutting-edge techniques, we concentrate and precisely deliver your own regenerative cells to areas in need of repair. This allows us to restore function and alleviate pain—without the need for surgery.

Our approach, known as regenerative orthopedic medicine, has helped thousands of people regain mobility and enjoy a more active, pain-free life. Let us help you break free from the cycle of pain and invasive treatments. Experience the power of your body’s natural healing ability today.

100%

Saw improvement in pain scores in just 1 month!

120 participant results measured in 1-month follow ups following mesenchymal stem cell injections, compared to baseline.

Up to 76% Average Function Regained and Overall Pain Improvement

Frequently Asked Questions

What are Mesenchymal Stem Cells (MSCs)

Mesenchymal Stem Cells (MSCs) are undifferentiated cells capable of developing into diverse cell lineages. These cells maintain the capacity for self-renewal and are highly responsive to their surrounding environment. Upon receiving specific signals, they commit to differentiation pathways, transforming into specialized cells like skin, muscle, cartilage, tendon, bone, or red blood cells. Augmenting the availability of stem cells at a site of injury or damage can significantly promote optimal tissue regeneration by ensuring an ample supply of cells for repair.

What makes mesenchymal stem cells (MSCs) useful in a clinical setting?

Mesenchymal stem cells (MSCs) are increasingly utilized in treating a range of diseases due to their remarkable properties. These include self-renewal (the ability to create more stem cells), differentiation (the process of maturing into specialized cells with distinct form and function; for example, an MSC can develop into various cell types), anti-inflammatory effects (reducing harmful inflammation), and immunomodulation (regulating the immune system). Immunomodulation is particularly important, as MSCs can both stimulate a weak immune response and dampen an overactive one, potentially preventing the autoimmune reactions seen in many disorders. The anti-inflammatory capabilities of MSCs are crucial, as while inflammation is a natural defense mechanism, chronic or excessive inflammation can damage the body.

Extensive research, including both in-vitro (laboratory-based) and in-vivo (within a living organism) studies, has supported the safety and efficacy of MSC therapy and continues to elucidate the underlying mechanisms. This research highlights the diverse capabilities of MSCs, enabling their use in a variety of clinical settings for numerous degenerative conditions.

Emerging evidence suggests that umbilical cord tissue-derived MSCs (UC-MSCs) may possess greater potency compared to MSCs from other sources, potentially leading to enhanced clinical effectiveness.

Are there ethical issues involving this form of stem cell therapy?

Adult mesenchymal stem cells (MSCs) do not raise the same ethical concerns as fetal and embryonic stem cells. Both the Catholic Church and the Southern Baptist Convention have endorsed the research and therapeutic use of adult stem cells as an ethically acceptable alternative.

Why use umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs)?

Advantages of Umbilical Cord Tissue-Derived Mesenchymal Stem Cells (UC-MSCs)

Umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) offer several advantages over other sources of MSCs, such as bone marrow-derived MSCs (BM-MSCs) and adipose-derived stem cells (ASCs):

  • Superior Proliferation: UC-MSCs exhibit a significantly higher proliferation rate in vitro (in a laboratory setting) compared to BM-MSCs and ASCs. This allows for more efficient expansion to obtain the large cell numbers needed for therapeutic applications.

  • Non-Invasive Harvesting: The collection of UC-MSCs is non-invasive. The cells are obtained from ethically donated umbilical cord tissue after birth, a process that poses no risk or discomfort to either the mother or the newborn. This contrasts with BM-MSC harvesting, which requires a bone marrow aspiration, and ASC harvesting, which typically involves liposuction.

  • Enhanced Secretion of Beneficial Factors: UC-MSCs secrete a variety of growth factors, cytokines, and chemokines. These secreted factors play a crucial role in tissue repair, reducing inflammation, and modulating the immune system.

  • Differentiation Potential: Like other MSCs, UC-MSCs can differentiate into various cell types, contributing to tissue regeneration.

  • Upregulated Genes: Research indicates that certain genes associated with cell proliferation (e.g., EGF), signaling pathways involved in cell survival and growth (e.g., PI3K-NFkB pathway via TEK), and neurogenesis (e.g., RTN1, NPPB, NRP2) are upregulated (have increased activity) in UC-MSCs compared to BM-MSCs. This suggests a potentially greater capacity for tissue repair and regeneration.

Is regenerative medicine being used to treat patients yet?

Yes! In recent years, several regenerative medicine treatments have been introduced into clinical practice for pain management and orthopedic care. These treatments utilize adult stem cells, making them non-controversial. The available procedures include:

  • Platelet-Rich Plasma (PRP) Therapy
  • Mesenchymal Stem Cell-Rich Injections
  • Bone Marrow-Derived Stem Cell Injections
  • Fat-Derived Stem Cell Injections

Regenerative medicine may offer benefits for various medical conditions, including:

    • Joint arthritis
    • Tennis elbow (lateral epicondylitis)
    • Golfer’s elbow (medial epicondylitis)
    • Rotator cuff tendonitis
    • Ligament sprains
    • Fractures
    • Tendon injuries
    • Cartilage defects
    • COPD
    • Kidney failure
    • Stroke
    • Multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS)
    • Dementia
    • Erectile dysfunction
    • Heart failure
    • Diabetes
    • Diabetic neuropathy
Is there any chance my body rejects mesenchymal stem cells (MSCs)?

MSCs possess immunosuppressive properties, reducing the likelihood of immune rejection compared to other foreign cells. Umbilical cord tissue-derived MSCs (UC-MSCs) are particularly immune-privileged, meaning they are universally accepted by the recipient’s body with virtually no risk of rejection. This is because UC-MSCs are essentially “new” and haven’t been “claimed” by a specific immune system. Unlike organ transplantation, UC-MSC therapy doesn’t require blood products or HLA matching.

Does insurance cover regenerative medicine therapy?

Regenerative medicine procedures are generally not covered by insurance. While some surgical applications may have billing codes, most treatments are considered out-of-pocket expenses.

How much do regenerative medcine treatments cost?

The price range for regenerative medicine injections is broad, typically between $1,500 and $7,500.

Who is a Candidate for Stem Cell Therapy?

Our protocol is designed to significantly reduce chronic low-grade inflammation over an extended period. Stem cells possess a unique ability to target areas of inflammation in the body. Research indicates that they can regenerate damaged or diseased tissues, decrease inflammation, and regulate the immune system—contributing to improved health and overall quality of life.

Studies suggest that mesenchymal stem cells (MSCs) may have a positive impact on various conditions, including:

  • ALS
  • Alzheimer’s disease
  • Autoimmune disorders
  • COPD and other degenerative/inflammatory lung diseases
  • COVID-19 (acute and long-haul)
  • Chronic inflammation
  • Crohn’s disease
  • Type 1 diabetes
  • Heart failure and heart disease
  • Kidney disease
  • Liver disease
  • Lupus
  • Lyme disease
  • Multiple sclerosis
  • Degenerative neurological conditions
  • Neuropathy
  • Parkinson’s disease
  • Reflex Sympathetic Dystrophy (RSD) / Complex Regional Pain Syndrome (CRPS)
  • Rheumatoid arthritis
  • Spinal cord injuries
  • Stroke (ischemic and hemiplegic)
  • Traumatic brain injury (TBI)
How many sessions will I need?

Our protocol aims for long-term stabilization of the condition with a single treatment. Follow-up treatments are not required. While some patients choose to return for additional treatments, typically seeking further improvement, generally one treatment is sufficient for most degenerative conditions.

Will the treatment be painful?

Patients generally report minimal discomfort during treatment, often describing the experience as painless. 

When will I start seeing results?

While individual responses vary, many study participants report noticeable improvements within 1-3 months after treatment. These improvements are evidenced by reduced systemic inflammation and increased vitality, as measured by follow-up questionnaires. Some patients report improvements in symptoms and quality of life even sooner, within the first few days post-treatment.

Do stem cells get trapped in the lungs? (Pulmonary first pass effect)

Umbilical cord-derived mesenchymal stem cells (UC-MSCs) are particularly effective for systemic delivery via intravenous infusion. Their optimal size (17-19 micrometers) allows for efficient passage through the circulatory system, including the lungs. Although a portion of MSCs may initially be trapped in the lungs (a phenomenon known as the pulmonary first-pass effect), this does not negate their therapeutic benefits. MSCs possess a remarkable homing ability – they can actively migrate to damaged tissues. Even while temporarily in the lungs, MSCs exert beneficial paracrine effects: they secrete growth factors and other molecules that reduce inflammation and stimulate tissue repair. Advances in research are continually enhancing the delivery and efficacy of MSCs for regenerative therapies.

Can stem cells help prevent aging?

Potential of Stem Cells in Anti-Aging and Rejuvenation

Current research suggests that stem cell therapies may have the potential to mitigate some effects of aging and improve overall healthspan. Stem cells, particularly mesenchymal stem cells (MSCs), possess properties that could contribute to this, including their ability to:

  • Repair damaged tissues: Stem cells can differentiate into various cell types, potentially replacing aged or damaged cells.
  • Reduce inflammation: Chronic inflammation is a key contributor to age-related decline, and MSCs have anti-inflammatory effects.
  • Modulate the immune system: MSCs can help regulate immune function, which often declines with age.
  • Homing Capability: Stem cells can migrate to sites of damage or inflammation.

The concept of a “protective shield” created by stem cells and anti-aging genes is a simplified representation of these complex biological processes. While a complete reversal of aging is not currently feasible, studies suggest that stem cell interventions, potentially in combination with therapies targeting aging-related genes, could contribute to a healthier and potentially longer lifespan. It’s crucial to understand that this is an area of ongoing research, and many claims about “anti-aging” stem cell treatments are not yet supported by robust clinical evidence.

Potential Benefits of Stem Cell Therapy (Observed and Reported):

Some reported benefits of stem cell therapies, particularly in the context of age-related decline, include:

  • Increased energy and vitality
  • Improved physical capacity and endurance
  • Improved hair quality and thickness
  • Enhanced libido
  • Pain reduction
  • Increased strength, balance, and overall mobility
  • Enhanced immune function
  • Overall improvement in quality of life
  • Reduced inflammatory markers
Can MSCs cause Graft vs. Host Disease?

Mesenchymal stem cells (MSCs) are not a cause of graft-versus-host disease (GVHD); in fact, they are being investigated as a potential treatment for this condition. GVHD is a serious complication that can occur after allogeneic hematopoietic stem cell transplantation (typically bone marrow or cord blood transplants), where the donor’s immune cells (T-cells) attack the recipient’s tissues.

MSCs possess immunomodulatory properties that make them promising candidates for GVHD therapy. They achieve this through several mechanisms, including:

  • Secretion of bioactive molecules: MSCs release proteins, peptides, and hormones that can suppress the immune response.
  • Mitochondrial transfer: MSCs can transfer mitochondria (the energy-producing components of cells) to damaged cells, potentially aiding in tissue repair.
  • Exosome and microvesicle release: MSCs release small vesicles containing RNA and other molecules that can influence the behavior of recipient cells, including immune cells.

While many studies suggest that MSC therapy can be beneficial for both acute and chronic GVHD, more extensive, large-scale, randomized controlled trials are needed to definitively confirm these findings and establish optimal treatment protocols.

It is important to clarify a distinction: although MSCs can modulate the activity of immune cells like T-lymphocytes and B-lymphocytes (reducing their proliferation and secretion of inflammatory factors), they are not broadly immunosuppressive in the same way as traditional immunosuppressant drugs. They have targeted immunomodulatory effects, rather than causing widespread immune suppression. This targeted effect is one reason they are promising for treating GVHD.

What is your success rate?

Follow-up vitality questionnaires indicate that approximately 85% of patients report sustained improvement in their condition within three months of treatment.

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