Rejuve Anti Aging Medical Spa in Rancho Santa Margarita

STEM CELL JOINT INJECTIONS

HIP PAIN

STEM CELL JOINT INJECTIONS

HIP PAIN

Regenerative medicine treatments may offer a superior alternative to hip surgery or hip replacement.

Rediscover pain-free movement with Rejuve Anti Aging’s cutting-edge regenerative therapies. Our advanced trifecta joint injections—combining PRP, Stem Cells, and Exosomes—offer a powerful, non-surgical solution for hip pain and joint injuries.

By activating your body’s natural healing abilities, these innovative treatments support tissue repair and regeneration, effectively addressing arthritis, labral tears, hip impingement, bursitis, and ligament injuries. Unlike conventional pain management, which merely masks symptoms, our regenerative approach targets the root cause—promoting lasting recovery and improved function.

Whether you’re an athlete striving to stay in peak condition, dealing with chronic hip discomfort, or looking to maintain mobility as you age, Rejuve’s regenerative solutions can help restore strength and flexibility. Experience a revitalized, pain-free lifestyle and potentially avoid the need for invasive surgery.

Skip the risks and long recovery of traditional hip surgery. Rejuve Anti Aging provides ultrasound-guided stem cell injections, a precise, image-assisted technique using your own Mesenchymal Stem Cells to repair damaged hip tissues. This state-of-the-art approach fosters natural healing and optimal function—without the trauma of surgery.

Labrum Tears - Hip Osteoarthritis - Hip Tendon Tears

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PROVEN RESULTS

Stem cell therapy: clinically proven to reduce joint pain and improve mobility.

NATURAL & SAFE

Leveraging the body’s own processes combined with PRP, Stem Cells and Exosomes

SIMPLE 30 MIN PROCEDURE

Ultrasound guided, highly accurate joint injections without anesthesia or downtime.

100% GUARANTEE OF HIP PAIN REDUCTION!

Details Available During The Consultation

Clinical Studies of Stem Cells and Hip Injuries

Over the past decade, there has been a significant surge in research and publications exploring the therapeutic use of mesenchymal stem cells (MSCs) for hip pain and related conditions. This expanding body of work underscores the growing interest and ongoing efforts to optimize this regenerative approach. Recent studies have increasingly focused on understanding the precise mechanisms of MSCs, shifting beyond their differentiation potential to examine their critical roles in paracrine signaling and immunomodulation. The rising number of clinical trials investigating MSC therapy for hip pain reflects a dedicated push to translate promising preclinical findings into real-world benefits for individuals suffering from chronic hip conditions and injuries.

"MSCs have shown sustained benefits and arrested the progression of osteoarthritis"

Journal of Regenerative Medicine

A comprehensive review of relevant studies and clinical trials for conditions such as Osteoarthritis (OA), Osteonecrosis (ONFH) and gluteal tendinopathy

"ALL showed reduction in pain and increase in functional ability across studies"

Journal of Stem Cells

The size of cartilage defect decreased while the volume of cartilage increased

"Proved to be a safe and clinically effective treatment in the restoration of hip function and range of motion"

Journal of Hip Preservation Surgery

The statistical significance of the  radiographic scores (Tönnis Classification of Osteoarthritis improved in all patients.

End Hip Pain!

Have you been told that the only way to relieve your hip pain is through steroid injections or invasive surgery?

Studies indicate that common hip surgeries, such as labral repairs and arthroscopic procedures, often provide limited long-term benefits and may be no more effective than conservative treatments. This raises concerns about their true effectiveness in alleviating pain and restoring function.

While hip replacements are sometimes necessary, they are highly invasive procedures with significant risks. The lengthy rehabilitation process and the potential for complications, including implant wear and adjacent joint stress, can contribute to long-term mobility challenges. Given these factors, exploring regenerative alternatives may offer a safer, more sustainable solution for hip pain and joint health.

Stem Cell Therapy Could Be The Exact Non-Surgical Alternative You’ve Been Waiting For!

Reclaim your active lifestyle. Rejuve Anti-Aging offers non-surgical solutions to get you back to the activities you love.

The fear is real: a sudden, sharp pain, your hip locking up, the struggle to stand or walk. The uncertainty of every step keeps you on edge, making you second-guess even the simplest movements. Imagine missing out on life’s most cherished moments—watching from the sidelines instead of dancing at a family gathering, hesitating to take a stroll with your partner, or avoiding travel because long walks feel impossible.

For months, the stiffness, instability, and discomfort have held you back, making everyday activities feel daunting. The looming thought of invasive hip surgery—with its long recovery and uncertain outcomes—only adds to the frustration. But what if there was a better way?

At Rejuve Anti Aging, we understand the challenges of hip pain and limited mobility. That’s why we offer cutting-edge, non-surgical regenerative therapies designed to activate your body’s natural healing abilities. With advanced treatments like PRP, Stem Cells, and Exosomes, we help restore stability, flexibility, and strength—so you can move freely and confidently, without the fear of surgery. Let us guide you toward a future of movement, independence, and lasting relief.

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Outcomes For Hip Stem Cell Procedures

Over the past decade, interest in mesenchymal stem cell (MSC) therapy for hip injuries has surged, with research and clinical trials accelerating to refine this groundbreaking treatment.

Recent breakthroughs extend beyond MSCs’ ability to regenerate tissue—scientists are now uncovering their powerful roles in paracrine signaling and immunomodulation. This deeper understanding is paving the way for more precise and effective regenerative therapies.

With clinical trials on the rise, the momentum to bring MSC therapy from the lab to real-world use is stronger than ever. The goal? To provide lasting relief for patients struggling with chronic hip pain, cartilage degeneration, and tendon injuries.

Function Regained
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Decrease In Pain 1 Month
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Overall Improvement 3 Months
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COMMON HIP CONDITIONS TREATED WITH STEM CELL JOINT INJECTIONS AT REJUVE ANTI AGING

  • Can Hip Pain from Osteoarthritis Be Treated Without Surgery?

    Hip pain is one of the most common symptoms of osteoarthritis, often impacting daily activities and overall quality of life. If you've been told that hip replacement surgery is your only option, Rejuve Anti Aging encourages you to explore non-surgical alternatives that may help you regain mobility and reduce pain.

    Osteoarthritis of the hip occurs due to degenerative changes in the joint’s cartilage, leading to discomfort, stiffness, and reduced function. Fortunately, regenerative therapies, such as stem cell treatments and PRF (Platelet-Rich Fibrin) injections, have shown promising results in reducing pain and supporting the body’s natural healing process—without the need for invasive surgery. These advanced treatments can offer faster recovery times, fewer complications, and a more natural approach to joint restoration.

    Non-Surgical Regenerative Therapy vs. Hip Replacement Surgery

    TreatmentRegenerative Therapy (e.g., PRF, Stem Cells)Hip Replacement Surgery
    Return to Daily Routine2 to 5 days6+ weeks
    Return to Sports/Exercise3 to 6 months1 year
    RecoveryMild soreness, minimal downtimeCrutches, brace, extensive rehab, no driving for months
    Pain ManagementOver-the-counter medication (days)Prescription pain medication (weeks)
    General AnesthesiaNoYes
    Preserves Natural Hip JointYesNo

    At Rejuve Anti Aging, we specialize in cutting-edge regenerative therapies designed to help you stay active and pain-free without the risks and downtime associated with surgery. If you're looking for a non-invasive alternative to hip replacement, schedule a consultation with us today to learn more about your options.

  • Understanding Hip Labrum Tears and Their Impact on Mobility

    Hip labrum tears can cause significant discomfort, limiting mobility and making everyday activities more challenging. The labrum is a soft cartilage ring that stabilizes the hip joint, and when it becomes damaged, it can lead to persistent pain, stiffness, and restricted movement.

    While athletes, dancers, and individuals with active lifestyles are more prone to hip labrum injuries, anyone can develop this condition. Repetitive movements, structural abnormalities, or even natural wear and tear can contribute to a tear in the labrum. Early recognition of symptoms and exploring treatment options are essential for preventing further complications and maintaining joint function.

    How the Hip Labrum Supports Joint Stability

    The hip labrum plays a critical role in hip function by lining the outer edge of the acetabulum (hip socket). This structure creates a secure seal around the joint, keeping the femoral head (thighbone) properly positioned and allowing for smooth, controlled movement.

    Beyond stability, the labrum also helps distribute pressure evenly across the joint, reducing friction between bones and enhancing flexibility. It acts as a shock absorber during activities like walking, running, and twisting, protecting the hip from excessive wear and tear.

    At Rejuve Anti Aging, we offer advanced regenerative therapies designed to promote healing and reduce pain caused by hip labrum injuries. If you're experiencing discomfort from a labral tear, contact us to learn more about our non-surgical treatment options.

    Risks of Hip Labrum Surgery: What You Should Know

    Hip labrum surgery comes with certain risks, and the long-term outcomes can vary. In many cases, surgical "cleanup" of a labral tear involves removing part of the labrum, which may actually increase the risk of joint degeneration and osteoarthritis over time.

    Because of these risks, it’s essential to explore all available treatment options before committing to surgery. At Rejuve Anti Aging, we offer non-surgical regenerative therapies that may help reduce pain, promote healing, and preserve your natural hip joint.

    Can You Treat a Hip Labral Tear Without Surgery?

    If you've been diagnosed with a hip labral tear and told that surgery is your only option, it's important to know that less invasive alternatives exist. Surgery isn’t always necessary, and regenerative treatments can provide a viable solution for pain relief and recovery.

    At Rejuve Anti Aging, we utilize cutting-edge regenerative therapies—such as PRF (Platelet-Rich Fibrin) and stem cell treatments—to address hip labrum injuries. Whether your tear is due to an acute injury or a degenerative condition, these treatments may support your body’s natural healing process while avoiding the risks and downtime associated with surgery.

    Non-Surgical Regenerative Therapy vs. Hip Labrum Surgery

    TreatmentRegenerative Therapy (e.g., PRF, Stem Cells)Hip Labrum Surgery
    Return to Daily Routine2 to 5 days6+ weeks
    Return to Sports/Exercise3 to 6 months1 year
    RecoveryMild soreness, minimal downtimeCrutches, brace, extensive rehab, no driving for months
    Pain ManagementOver-the-counter medication (days)Prescription pain medication (weeks)
    General AnesthesiaNoYes
    Preserves Natural Hip LabrumYesNo

    If you’re looking for a non-invasive alternative to hip labrum surgery, Rejuve Anti Aging can help. Contact us today to learn more about our regenerative therapies and find out if you’re a candidate for non-surgical treatment.

     
  • Traditional Treatments for Hip Tendon Injuries & Their Risks

    When dealing with hip tendon injuries, most physicians initially recommend conservative treatments such as rest, ice, anti-inflammatory medications, massage, stretching, and strengthening exercises through physical therapy. If symptoms persist, more invasive options like corticosteroid injections or hip tendon repair surgery may be suggested.

    The Risks of Hip Tendon Repair Surgery

    Hip tendon repair surgery can involve stitching torn tendons, cutting the tendon to encourage healing, or lengthening a tight tendon. While these procedures may provide temporary pain relief, altering the tendon’s structure can often lead to further complications, including:

    • Permanent damage to surrounding ligaments, muscles, and fascia

    • Chronic pain that persists even after surgery

    • Chromosomal damage from metal debris associated with hip replacements

    • Cobalt and chromium toxicity from metal implants

    • Tissue irritation that may lead to pseudotumors (abnormal growths caused by irritation from hip replacement materials)

    • Allergic reactions to surgical materials used in hip repair procedures

    • Hip instability, increasing the risk of future injuries

    Additionally, surgery does not address the underlying biomechanical issues—such as hip impingement, tendonitis, arthritis, or labral tears—that contributed to the injury in the first place. Because tendons naturally have a poor blood supply, they may not heal well post-surgery, making reinjury a significant risk.

    A Non-Surgical Alternative at Rejuve Anti Aging

    Rather than resorting to invasive procedures, regenerative therapies such as PRF (Platelet-Rich Fibrin) and stem cell treatments offer a non-surgical approach to promoting natural healing, reducing pain, and restoring function. These advanced treatments harness the body’s own healing mechanisms to address the root cause of tendon injuries without the long-term risks of surgery.

    If you’re considering your options for hip tendon repair, contact Rejuve Anti Aging to explore innovative, non-invasive solutions tailored to your needs.

     

HIP JOINT HEALTH

The human body is designed to heal itself. Your body’s natural goal is repair and regeneration. A simple example is when you get a cut—your body stops the bleeding, forms a scab, and sends healing cells to close the wound.

This self-healing ability is constantly at work, even when you can’t see it. Your body is always scanning for damage and sending repair cells where they’re needed. However, certain factors influence how effectively your body can heal, including:

  • Smoking habits
  • Alcohol consumption
  • Sleep quality and duration
  • Regular physical activity
  • Nutrition and digestion
  • Stress management

Even with a healthy lifestyle—eating well, exercising, and getting enough rest—there are times when your body needs extra support. That’s where regenerative therapies at Rejuve Anti Aging can help. Our advanced treatments, including stem cell therapy and PRF, work with your body’s natural healing processes to restore function, reduce pain, and promote long-term wellness.

AND THAT’S WHERE REJUVE ANTI AGING CAN HELP!

REGENERATIVE MEDICINE AND HIP PAIN

Modern medicine often relies on medications that only mask pain rather than promoting true healing. Too many people are prescribed surgeries that may not effectively resolve their pain or the underlying problem.

Surgery itself is highly invasive—requiring tools that seem better suited for a construction site than the human body. That’s why it’s called surgical reconstruction. Recovery can take months or even years, and in many cases, the joint never fully feels or functions as it once did.

Joint replacement surgery introduces foreign materials into the body, which can create long-term issues. Just like your body reacts to a splinter—trying to push it out—your immune system may respond to implants with inflammation and pain, as it doesn’t recognize them as part of its natural structure.

At Rejuve Anti Aging, our regenerative therapies work with your body’s natural healing abilities. Using cutting-edge techniques, we concentrate and precisely deliver your body’s own regenerative cells to areas in need of repair, helping to restore function and reduce pain—without surgery. This approach, known as regenerative orthopedic medicine, has helped thousands regain mobility and live more active, pain-free lives.

100%

Saw improvement in pain scores in just 1 month!

120 participant results measured in 1-month follow ups following mesenchymal stem cell injections, compared to baseline.

Up to 76% Average Function Regained and Overall Pain Improvement

Frequently Asked Questions

What are Mesenchymal Stem Cells (MSCs)

Mesenchymal Stem Cells (MSCs) are undifferentiated cells capable of developing into diverse cell lineages. These cells maintain the capacity for self-renewal and are highly responsive to their surrounding environment. Upon receiving specific signals, they commit to differentiation pathways, transforming into specialized cells like skin, muscle, cartilage, tendon, bone, or red blood cells. Augmenting the availability of stem cells at a site of injury or damage can significantly promote optimal tissue regeneration by ensuring an ample supply of cells for repair.

What makes mesenchymal stem cells (MSCs) useful in a clinical setting?

Mesenchymal stem cells (MSCs) are increasingly utilized in treating a range of diseases due to their remarkable properties. These include self-renewal (the ability to create more stem cells), differentiation (the process of maturing into specialized cells with distinct form and function; for example, an MSC can develop into various cell types), anti-inflammatory effects (reducing harmful inflammation), and immunomodulation (regulating the immune system). Immunomodulation is particularly important, as MSCs can both stimulate a weak immune response and dampen an overactive one, potentially preventing the autoimmune reactions seen in many disorders. The anti-inflammatory capabilities of MSCs are crucial, as while inflammation is a natural defense mechanism, chronic or excessive inflammation can damage the body.

Extensive research, including both in-vitro (laboratory-based) and in-vivo (within a living organism) studies, has supported the safety and efficacy of MSC therapy and continues to elucidate the underlying mechanisms. This research highlights the diverse capabilities of MSCs, enabling their use in a variety of clinical settings for numerous degenerative conditions.

Emerging evidence suggests that umbilical cord tissue-derived MSCs (UC-MSCs) may possess greater potency compared to MSCs from other sources, potentially leading to enhanced clinical effectiveness.

Are there ethical issues involving this form of stem cell therapy?

Adult mesenchymal stem cells (MSCs) do not raise the same ethical concerns as fetal and embryonic stem cells. Both the Catholic Church and the Southern Baptist Convention have endorsed the research and therapeutic use of adult stem cells as an ethically acceptable alternative.

Why use umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs)?

Advantages of Umbilical Cord Tissue-Derived Mesenchymal Stem Cells (UC-MSCs)

Umbilical cord tissue-derived mesenchymal stem cells (UC-MSCs) offer several advantages over other sources of MSCs, such as bone marrow-derived MSCs (BM-MSCs) and adipose-derived stem cells (ASCs):

  • Superior Proliferation: UC-MSCs exhibit a significantly higher proliferation rate in vitro (in a laboratory setting) compared to BM-MSCs and ASCs. This allows for more efficient expansion to obtain the large cell numbers needed for therapeutic applications.

  • Non-Invasive Harvesting: The collection of UC-MSCs is non-invasive. The cells are obtained from ethically donated umbilical cord tissue after birth, a process that poses no risk or discomfort to either the mother or the newborn. This contrasts with BM-MSC harvesting, which requires a bone marrow aspiration, and ASC harvesting, which typically involves liposuction.

  • Enhanced Secretion of Beneficial Factors: UC-MSCs secrete a variety of growth factors, cytokines, and chemokines. These secreted factors play a crucial role in tissue repair, reducing inflammation, and modulating the immune system.

  • Differentiation Potential: Like other MSCs, UC-MSCs can differentiate into various cell types, contributing to tissue regeneration.

  • Upregulated Genes: Research indicates that certain genes associated with cell proliferation (e.g., EGF), signaling pathways involved in cell survival and growth (e.g., PI3K-NFkB pathway via TEK), and neurogenesis (e.g., RTN1, NPPB, NRP2) are upregulated (have increased activity) in UC-MSCs compared to BM-MSCs. This suggests a potentially greater capacity for tissue repair and regeneration.

Is regenerative medicine being used to treat patients yet?

Yes! In recent years, several regenerative medicine treatments have been introduced into clinical practice for pain management and orthopedic care. These treatments utilize adult stem cells, making them non-controversial. The available procedures include:

  • Platelet-Rich Plasma (PRP) Therapy
  • Mesenchymal Stem Cell-Rich Injections
  • Bone Marrow-Derived Stem Cell Injections
  • Fat-Derived Stem Cell Injections

Regenerative medicine may offer benefits for various medical conditions, including:

    • Joint arthritis
    • Tennis elbow (lateral epicondylitis)
    • Golfer’s elbow (medial epicondylitis)
    • Rotator cuff tendonitis
    • Ligament sprains
    • Fractures
    • Tendon injuries
    • Cartilage defects
    • COPD
    • Kidney failure
    • Stroke
    • Multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS)
    • Dementia
    • Erectile dysfunction
    • Heart failure
    • Diabetes
    • Diabetic neuropathy
Is there any chance my body rejects mesenchymal stem cells (MSCs)?

MSCs possess immunosuppressive properties, reducing the likelihood of immune rejection compared to other foreign cells. Umbilical cord tissue-derived MSCs (UC-MSCs) are particularly immune-privileged, meaning they are universally accepted by the recipient’s body with virtually no risk of rejection. This is because UC-MSCs are essentially “new” and haven’t been “claimed” by a specific immune system. Unlike organ transplantation, UC-MSC therapy doesn’t require blood products or HLA matching.

Does insurance cover regenerative medicine therapy?

Regenerative medicine procedures are generally not covered by insurance. While some surgical applications may have billing codes, most treatments are considered out-of-pocket expenses.

How much do regenerative medcine treatments cost?

The price range for regenerative medicine injections is broad, typically between $1,500 and $7,500.

Who is a Candidate for Stem Cell Therapy?

Our protocol is designed to significantly reduce chronic low-grade inflammation over an extended period. Stem cells possess a unique ability to target areas of inflammation in the body. Research indicates that they can regenerate damaged or diseased tissues, decrease inflammation, and regulate the immune system—contributing to improved health and overall quality of life.

Studies suggest that mesenchymal stem cells (MSCs) may have a positive impact on various conditions, including:

  • ALS
  • Alzheimer’s disease
  • Autoimmune disorders
  • COPD and other degenerative/inflammatory lung diseases
  • COVID-19 (acute and long-haul)
  • Chronic inflammation
  • Crohn’s disease
  • Type 1 diabetes
  • Heart failure and heart disease
  • Kidney disease
  • Liver disease
  • Lupus
  • Lyme disease
  • Multiple sclerosis
  • Degenerative neurological conditions
  • Neuropathy
  • Parkinson’s disease
  • Reflex Sympathetic Dystrophy (RSD) / Complex Regional Pain Syndrome (CRPS)
  • Rheumatoid arthritis
  • Spinal cord injuries
  • Stroke (ischemic and hemiplegic)
  • Traumatic brain injury (TBI)
How many sessions will I need?

Our protocol aims for long-term stabilization of the condition with a single treatment. Follow-up treatments are not required. While some patients choose to return for additional treatments, typically seeking further improvement, generally one treatment is sufficient for most degenerative conditions.

Will the treatment be painful?

Patients generally report minimal discomfort during treatment, often describing the experience as painless. 

When will I start seeing results?

While individual responses vary, many study participants report noticeable improvements within 1-3 months after treatment. These improvements are evidenced by reduced systemic inflammation and increased vitality, as measured by follow-up questionnaires. Some patients report improvements in symptoms and quality of life even sooner, within the first few days post-treatment.

Do stem cells get trapped in the lungs? (Pulmonary first pass effect)

Umbilical cord-derived mesenchymal stem cells (UC-MSCs) are particularly effective for systemic delivery via intravenous infusion. Their optimal size (17-19 micrometers) allows for efficient passage through the circulatory system, including the lungs. Although a portion of MSCs may initially be trapped in the lungs (a phenomenon known as the pulmonary first-pass effect), this does not negate their therapeutic benefits. MSCs possess a remarkable homing ability – they can actively migrate to damaged tissues. Even while temporarily in the lungs, MSCs exert beneficial paracrine effects: they secrete growth factors and other molecules that reduce inflammation and stimulate tissue repair. Advances in research are continually enhancing the delivery and efficacy of MSCs for regenerative therapies.

Can stem cells help prevent aging?

Potential of Stem Cells in Anti-Aging and Rejuvenation

Current research suggests that stem cell therapies may have the potential to mitigate some effects of aging and improve overall healthspan. Stem cells, particularly mesenchymal stem cells (MSCs), possess properties that could contribute to this, including their ability to:

  • Repair damaged tissues: Stem cells can differentiate into various cell types, potentially replacing aged or damaged cells.
  • Reduce inflammation: Chronic inflammation is a key contributor to age-related decline, and MSCs have anti-inflammatory effects.
  • Modulate the immune system: MSCs can help regulate immune function, which often declines with age.
  • Homing Capability: Stem cells can migrate to sites of damage or inflammation.

The concept of a “protective shield” created by stem cells and anti-aging genes is a simplified representation of these complex biological processes. While a complete reversal of aging is not currently feasible, studies suggest that stem cell interventions, potentially in combination with therapies targeting aging-related genes, could contribute to a healthier and potentially longer lifespan. It’s crucial to understand that this is an area of ongoing research, and many claims about “anti-aging” stem cell treatments are not yet supported by robust clinical evidence.

Potential Benefits of Stem Cell Therapy (Observed and Reported):

Some reported benefits of stem cell therapies, particularly in the context of age-related decline, include:

  • Increased energy and vitality
  • Improved physical capacity and endurance
  • Improved hair quality and thickness
  • Enhanced libido
  • Pain reduction
  • Increased strength, balance, and overall mobility
  • Enhanced immune function
  • Overall improvement in quality of life
  • Reduced inflammatory markers
Can MSCs cause Graft vs. Host Disease?

Mesenchymal stem cells (MSCs) are not a cause of graft-versus-host disease (GVHD); in fact, they are being investigated as a potential treatment for this condition. GVHD is a serious complication that can occur after allogeneic hematopoietic stem cell transplantation (typically bone marrow or cord blood transplants), where the donor’s immune cells (T-cells) attack the recipient’s tissues.

MSCs possess immunomodulatory properties that make them promising candidates for GVHD therapy. They achieve this through several mechanisms, including:

  • Secretion of bioactive molecules: MSCs release proteins, peptides, and hormones that can suppress the immune response.
  • Mitochondrial transfer: MSCs can transfer mitochondria (the energy-producing components of cells) to damaged cells, potentially aiding in tissue repair.
  • Exosome and microvesicle release: MSCs release small vesicles containing RNA and other molecules that can influence the behavior of recipient cells, including immune cells.

While many studies suggest that MSC therapy can be beneficial for both acute and chronic GVHD, more extensive, large-scale, randomized controlled trials are needed to definitively confirm these findings and establish optimal treatment protocols.

It is important to clarify a distinction: although MSCs can modulate the activity of immune cells like T-lymphocytes and B-lymphocytes (reducing their proliferation and secretion of inflammatory factors), they are not broadly immunosuppressive in the same way as traditional immunosuppressant drugs. They have targeted immunomodulatory effects, rather than causing widespread immune suppression. This targeted effect is one reason they are promising for treating GVHD.

What is your success rate?

Follow-up vitality questionnaires indicate that approximately 85% of patients report sustained improvement in their condition within three months of treatment.

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